CytomX Therapeutics

CytomX Therapeutics is an early-stage, privately funded biotechnology company developing Probodies^™, proteolytically activated antibodies. Probodies, by their ability to site-direct the activity of antibodies, will result in an improved therapeutic index for validated targets as well as enable the drugging of targets with broad tissue expression. The mission of CytomX Therapeutics, alone and with the help of partners, is to provide patients with more effective and less toxic therapies for severe illnesses such as cancer and inflammatory diseases.

FiReSpotter: John Petote, CEO, CIO Solutions

HOANA

Launched in 2002, Hoana Medical Inc. ("Hoana") has raised $40 million in private equity to build the world's leading healthcare company focused on Intelligent Medical Vigilance. Today, Hoana manufactures and sells a unique life-saving medical technology called the LifeBed^™ Patient Vigilance System, a reusable-disposable ("reposable") mattress coverlet that tracks a patient's basic vital signs without any wires or connection to the patient. Hoana recently introduced a new version of the LifeBed focused on emergency room overcrowding, called the LifeGurney^™ Patient Vigilance System.

Each year, approximately 200,000 people die in U.S. hospitals from errors and mistakes, with nearly 40% of all unanticipated deaths occurring on medical-surgical floors of acute-care hospitals ("Transforming Care at the Bedside," Robert Wood Johnson Foundation, 2006). A recent study showed that your "odds of survival from a heart attack are better in a casino than in a hospital" ("Survival from In-Hospital Cardiac Arrests During Nights & Weekends," Journal of the American Medical Association, Peberdy et al., February 20, 2008).

Hoana's technology can transform any hospital bed into a LifeBed or LifeGurney. Since receiving U.S. Food & Drug Administration clearance in 2006, the LifeBed has been used by over 35,000 medical/surgical acute-care patients, resulting in hundreds of life-saving patient interventions.

FiReSpotter: VC Partner: Michael Pfeffer; Managing Partner, Kolohala Ventures

InTouch Health

InTouch Health is a leading provider of Remote Presence (RP) telehealth solutions which empower physicians to easily and more frequently visit with hospital-based patients. Wherever access to medical expertise is limited, RP can effectively extend the physician's reach to manage patient care, thereby removing time and distance barriers. With expertise available at a moment's notice, RP allows for innovative healthcare delivery models leading to improved quality of care.

InTouch Health offers a suite of RP products and solutions to meet the needs of every healthcare institution. Over one network and through a single interface, physicians can access a host of RP devices to provide care into EDs, ICUs, patient wards, operating rooms, and procedure rooms.

FiReSpotter: John Petote, CEO, CIO Solutions

Sea Breeze Power Corp.

Sea Breeze Power Corp. is focused on expediting widespread adoption of renewable energy at the utility scale.

Sea Breeze was the first company to initiate development of wind power generation in British Columbia. Through a joint venture with Boundless Energy LLC, the company has undertaken several leadership initiatives throughout Western North America in the development of strategic transmission projects to improve market access for renewable resources.

The company's flagship transmission project, the Juan de Fuca Cable, will connect the British Columbia transmission grid at Victoria, British Columbia, with an undersea cable to the Bonneville Power AdministrationÕs transmission system at Port Angeles, Washington. The Juan de Fuca Cable project was the first independently developed international transmission line to have received full permits from both Canada's National Energy Board and the U.S. Department of Energy. Construction, expected to be completed within two years, is planned to begin in 2010.

The Juan de Fuca Cable will use High Voltage Direct Current Light^® ("HVDC Light^®") technology, which offers environmental attributes such as the elimination of fluctuating electromagnetic fields, and provides speed and responsiveness ideally suited for digital control and support of Smart Grid applications and for integration of intermittent renewable resources.

Sea Breeze Power Corp.'s internal goals are to achieve superior, long-term financial returns for its shareholders and investors and to provide a satisfying, supportive, and well-compensated working environment for its staff and management.

Serious Materials

Serious Materials develops and manufactures sustainable green building materials that dramatically reduce the impact of the "built environment" on the climate.

The company was voted #1 at Cleantech Venture Forum XII, and won the first Aspen Institute award for innovation in Corporate Energy Conservation and Global Gypsum Product of the Year. It has also been recognized by TIME/CNN, Fortune, BusinessWeek, AlwaysOn, and more, as one of the most promising green companies.

Serious Materials aims for breakthroughs in product performance, without requiring changes in customer behavior or in how products are used - thus speeding market adoption.

FiReSpotter: Forest Baskett, General Partner, New Enterprise Associates

SkyFiber Inc.

SkyFiber Inc. develops patented wireless light communication products that address the rapidly growing global requirements for fast, secure, and affordable wireless communication solutions. SKYFIBER ^™ solutions can economically augment or replace traditional fiberoptic and microwave technologies to meet customer needs for mobility backhaul, enterprise, and campus area networks; last-mile connectivity; secure private data networks; and emergency response networks.

Drawing on the strength of a deep patent portfolio, SKYFIBER has overcome the reliability and distance limitations of earlier generations of free space optics (FSO) technologies. In customer implementations, SKYFIBER products have delivered 99.999% reliability, even in extraordinarily heavy fog, rain, and smog conditions. Additional SKYFIBER benefits include:

• Deployment in a fraction of the time and cost required for traditional solutions such as fiberoptics and microwave communication
• No FCC licensing requirements
• Industry's smallest physical footprint, reducing the complexities of zoning, site access, and lease costs
• Patented separation of antenna and electronics, requiring no rooftop power
• Zero RF footprint, ensuring the most secure network transmission available
• Lower power consumption and elimination of microwave smog results in an eco-friendly "green" solution
• Exclusive patent for Point to Multipoint (PtMP) mesh networking

Tesla Motors

At the core of Tesla Motors is the belief that an electric car need not be a driving sacrifice. Tesla has brought the best of the automotive and technology worlds together to permanently bury the image of an electric car as a step backward in performance, efficiency, or design. Its key technology is the 100% electric powertrain, which propels the company in the present and simultaneously establishes a foundation for its future models. Tesla sets out to forever alter perceptions of electric vehicles and to make electric cars a viable alternative. It has produced a car that is at once beautiful and exciting to drive, along with being the most efficient production automobile on the planet.

Twisted Pair Solutions

Twisted Pair Solutions created WAVE^®, a communications software platform that brings groups together for critical communications. By enabling Unified Group Communications, WAVE is powering the next generation of communications, collaboration, and interoperability solutions.

The WAVE software platform is a standards-based technology that unifies radio and other group communications systems over IP to achieve interoperability. Used by defense, federal, public safety, and commercial customers worldwide, WAVE is best known for its ability to extend and link private two-way radio networks so that users can communicate more effectively. WAVE is used in tactical command and control, dispatch operations, and multi-agency emergency management scenarios, protecting lives and transforming business operations.

Twisted Pair maintains an active ecosystem of partners, building WAVE-powered products, services, and solutions for a broad set of markets and customers. WAVE enables interoperable communications among telephony, collaboration, and messaging systems with group communications systems such as push-to-talk radio, intercom, paging, and broadcast systems, regardless of their underlying technology.